The MagLab is funded by the National Science Foundation and the State of Florida.
The MagLab is funded by the National Science Foundation and the State of Florida.
Neutralization-reionization mass spectrometry (MS) is of unique value for preparing and characterizing highly reactive and unstable neutral species.
These include the intermediate in the dissociative-recombination reaction H3O+ + e- → H2O + H + 6.4 eV. Following an earlier suggestion, using neutralization accompanying surface-induced dissociation (SID) to form an unstable site did not yield new cleavage reactions in multiply charged protein cations from electrospray ionization (ESI) with Fourier transform (FT) MS.
B. A. Cerda, et al, Electron Capture Dissociation of Multiply Charged Proten Cations. A Nonergodic Process, Journal of the American Chemical Society 120, 3265-3266 (1998) Read online.
Explore our magnet schedule to see what exciting research is happening on our stellar fleet of instruments right now.
Y. Mao, et al, Top-Down Structural Analysis of an Intact Monoclonal Antibody by Electron Capture Dissociation-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry, Analytical Chemistry 85(9) pp 4239-4246 (2013) Read online.
For more information please contact Lissa Anderson.
Last modified on 08 August 2023
